After the disease is removed surgically, whatever is left is microscopically and intraventricularly fought via intraperitoneal chemotherapy, the main goal of which is to eliminate any remaining free cancel cells. This is a specialized way of chemotherapy, applying the combined action of pharmaceutical substances and chemotherapy that acts selectively in the area of interest. Intraperitoneal chemotherapy has been proven highly effective since it manages to go through the "barrier" that impedes chemotherapy drugs from acting in the best way possible when these are administered intravenously. This technique has many benefits, resulting from the high temperature as well as from the anatomical place the operation takes place at.
High temperature offers the ability to fight the tumor, enables the infiltration of some drugs inside the cells and at the same time strengthens its action inside them. The anatomical position of the entire procedure (intraventricularly) allows the exposure of the disease to high doses of antineoplastic drugs, reducing their general adverse effects to the minimum. This dosage can be hundreds (some time thousands) of times bigger than the one used when administered intravenously, since, due to the peritoneal barrier, it is not absorbed into the systematic circulation.
The effect of hyperthemia to the antineoplastic action of drugs.
The effectiveness of chemotherapy has already been proven in the treatment of the peritoneal mesothelioma and pseudomyxoma (rare neoplasms), but studies have shown that it is also effective in the therapeutic treatment of large intestine cancer, stomach cancer and ovary cancer. Further research that will help with their conclusions to the prevention as well as development of the aforementioned diseases are underway.